| Specifications |
| |
TLC: |
One ninhydrin positive spot, phosphorus negative |
| Solubility |
| |
Soluble: |
Chloroform |
| |
Insoluble: |
Ethanol, Acetone, Water |
| Stability |
| |
Storage: |
-20°C |
| |
Shelf Life: |
12 Months |
| Preparation |
|
Avanti's sphingosine is prepared from sphingomyelin. The hydrolysis
of the phosphocholine and the fatty amide is performed by processes that
do not alter the stereochemistry of the sphingosine molecule. The product
is isolated by high-performance liquid chromatography. |
| Reference |
|
Kahn et al, W.A.,(1991), "Use of D-Erythro-sphingosine as a Pharmacological
Inhibitor of Protein Kinase-C in Human Platelets," Biochemical Journal 278, 387-392. |
|