| Animal and Tissue Source |
| |
Prepared from sheep deficient in ß galactosidase that have GM1 gangliosidosis.
Sheep are raised in USA and the flock is enrolled in the USDA Scrapie-free certification program.
The feed supply contains no animal parts, and the brain tissue is harvested 150 days after birth.
|
| Ganglioside Specifications |
| |
Product Type: |
Native product; no enzymatic manipulation of total gangliosides to produce GM1. |
| |
Purity: |
>99% by normal phase silica gel HPLC, ELSD detector. |
| |
Ceramide Content: |
Most abundant, d18:1 - C18:0; Minor d20:1 - C18:0 and d18:1 - C20:0. An estimation of the abundance of the three species is 70:25:5. |
| |
Sugar Content: |
Consistent with structure. |
| |
Salt Form: |
Ammonium. |
| |
Calcium Ion Content: |
<1000 ppm. |
| Physical Properties |
| |
Solubility: |
Soluble in various mixtures of Chloroform:Methanol:Water & Ethanol:Water. |
| |
Molecular Weight: |
Major Species 1545.0, Minor Species 1573.2. |
| |
CMC: |
2.0 x 10-8M. |
| References |
|
Characterization of the activation of rat liver beta-glucosidase by sialosylgangliotetraosylceramide.
Basu A, Glew RH.
J Biol Chem. 1985 Oct 25;260(24):13067-73.
[PubMed]
|
