700
Industrial Park Drive
Alabaster, AL 35007
1-800-227-0651 or 205-663-2494
Fax 1-800-229-1004 or 205-663-0756
Orders:
Technical Questions:
General
Information:
Summary
We have synthesized a diacyl lipid (DPGG) with a polyphenolic
head group. When hydrated, at
room temperature, DPGG forms gel (L) phase bilayers that
strongly adhere to each other. Since
polyphenolic compounds such as tannic acid bind and precipitate
a variety of lipids, proteins, and
polymers, DPGG bilayers are likely to be able to bind and
tether proteins and membranes.
Reprinted from Chemistry and Physics of Lipids with permission
from Elsevier Science.
Pollastri, M.P., N.A. Porter, T.J. McIntosh, and S.A. Simon.
Chem Phys Lipids 104:67-74.104 (2000)
67-74. Refer to abstract below.
Thermal Properties of DPGG and related lipidsa
Thermal
Properties of DPGG and related lipidsa
Lipid
Tpre
DHpre
Tm
DHm
DPGG
52.5, 55.4
-3.7
69.3
11.3
NPGS
52
-0 to -8b
82
17.5
DPPC
34.9
1.5
41
8.3
DPPE
64
8.5
Legend:
Tpre:
Exothermic pretransition peaks (°C)
DHpre:
Total enthalpy of pretransition peaks (kcal/mol)
Tm:
Main endothermic transition (°C)
DHm:
Total enthalpy of main endothermic transition (kcal/mol)
a NPGS data are from Ruocco
et al. (1981) and DPPE data are from Marsh (1990). b Depends on the scan rate and
thermal history.
Table reprinted from Chemistry and
Physics of Lipids with permission from Elsevier
Science.
References:
Pollastri, M.P., N.A. Porter, T.J. McIntosh, and S.A. Simon. (2000). Synthesis, structure, and thermal properties of
1,2-dipalmitoylgalloylglycerol (DPGG), a novel self-adhering lipid. Chem Phys Lipids 104:67-74. [PubMed]
