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Synthetic Products
Inhibitor of PKC
1,2-Diacyl Ethylene Glycol

Purity >99%
Typical Diacyl Ethylene Glycol Structure
1,2-Dioleoyl Ethylene Glycol (18:1 EG)

Product
M.W.
Catalog Number
1,2-Dioctanoyl Ethylene Glycol (8:0 EG)
314.47
800600
1,2-Dicapryl Ethylene Glycol (10:0 EG)
370.57
800601
1,2-Dilauroyl Ethylene Glycol (12:0 EG)
426.68
800602
1,2-Dimyristoyl Ethylene Glycol (14:0 EG)
482.79
800603
1,2-Dipalmitoyl Ethylene Glycol (16:0 EG)
538.90
800604
1,2-Dioleoyl Ethylene Glycol (18:1 EG)
590.97
800605
Specify Chloroform or Powder for these products

Preparation
Esterification of ethylene glycol with appropriate fatty acid.
Specifications for 1,2-Diacyl Ethylene Glycol
Physical Examination
TLC: Migrate as one spot
GC: >99% (AUC) of appropriate fatty acid
HPLC: >99% (AUC) of ethyleneglycol
FTIR: Correspond to appropriate reference standard
Solubility
Soluble: ethanol, methanol, chloroform, dimethyl sulfoxide
Insoluble: water
Stability
Shelf Life: Saturated, 12 months ~ Unsaturated, 6 months
Storage: -20°C

Note
Ethyleneglycols are conveniently stored in chloroform solutions in glass vials with teflon-lined caps at -20°C .

Reference

  1. Bishop, W.R., Ganong, B.R. & Bell, R.M., (1986), "Attenuation of sn-1,2-diacylglycerol Second Messengers by Diacylglycerol Kinase: Inhibition by Diacylglycerol Analogs in vitro and in Human Platelets", J. Biol. Chem. 261, 6993-7000.

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