700
Industrial Park Drive
Alabaster, AL 35007
1-800-227-0651 or 205-663-2494
Fax 1-800-229-1004 or 205-663-0756
Orders:
Technical Questions:
General
Information:
Avanti's nitroxide spin product listing is a group
of compounds designed to act as membrane probes. A variety
of positions down the hydrophobic chain are labeled with the
nitroxide functional groups. This family of compounds allows
probing the membrane at various depths. These compounds have
been synthesized from the 1-palmitoyl-2-hydroxy-sn-glycerol-3-phosphocholine
and the product is purified by HPLC.
References
Parce, J.W. & McConnell, H.M., (1980), "Kinetics
of antibody-dependent activation of the first component
of complement of lipid bilayer membranes," Biochem.
Biophy. Res. Co. 93, 235-242.
Balakrishnan, K., Hsu, F.J., Hafeman, D.G. & McConnell,
H.M., (1982), "Monoclonal antibodies to a nitroxide
lipid hapten", Biochem. Biophys. Acta 721,
30-38.
Chan, H.C., Magin, R.L. & Swartz, H.M.,(1988),
"Delivery of nitroxide spin label to cultured cells
by liposomes", Magazine Resonance in Medicine
8, 160-170.
Yin, Y.L. & Hyde, J.S., (1989), "Use of high
observing power in electron spin resonance saturation-recovery
experiments in spin-labeled membranes", Journal
of Chem. Phys 91, 6029-6035.
Dejongh, H.H.J., Hemminga, M.A. & Marsh, D., (1990),
"ESR of spin-labeled bacteriophage M13 coat protein
in mixed phospholipid bilayers", Biochem. Biophys.
Acta 1024, 82-88.
