|
Specifications
for Phosphatidylcholine
|
| Physical Examination |
|
Powder: |
White solid which contains no foreign matter and
no more than a faint odor. |
|
Organic Solution: |
Clear, colorless solution which contains no foreign
matter. |
| Identification |
|
GC: |
The retention time of the principal peak of the
sample chromatogram agrees with that of the chromatogram for
the reference standard. |
|
TLC: |
The Rf value and general appearance
of the principal peak of the sample chromato- gram agrees with
that of the reference standard. |
|
HPLC: |
The retention time of the principal peak of the
sample chromatogram for the refer- ence standard. |
|
FTIR: |
The infrared absorption spectrum of the sample
exhibits maxima only at the same wavelengths as that of the
standard between the regions of 4000-500 cm-1. |
|
UV/Visible: |
The UV/Visible absorption spectrum of the sample
exhibits maxima only at the same wavelengths as that of the
standard between the regions of 190-820 nm. |
| Chromatographic Purity |
|
GC: |
Not less than 99.0% (AUC). |
|
HPLC: |
Not less than 99.0% (AUC). |
| Specifications |
|
TLC: |
One phosphorus positive spot |
|
GC: |
Conforms to appropriate standard |
|
HPLC: |
>99% diacyl compound |
| Solubility |
|
Short Chain Saturated
(C3-C8) |
|
Soluble: |
Chloroform, Water |
|
Insoluble: |
Acetone |
|
Long
Chain Saturated (C9-C24) |
|
Soluble: |
Chloroform, Toluene, Methanol, Ethanol |
|
Insoluble: |
Acetone, Water |
|
Long
Chain Unsaturated
(C14-C24) |
|
Soluble: |
Chloroform, Toluene, Methanol,Ethanol |
|
Insoluble: |
Acetone, Water |
| Stability |
|
Storage: |
-20°C |
|
Shelf Life: |
3 months - Polyene
~ 6 months - Monoene
~ 12 months - Saturated |
Description:
The list of Phosphatidylcholine products offered by
Avanti
is designed to provide compounds having a variety of physical properties.
Products available include
short chain (C3-C8 are water soluble and hygroscopic),
saturated, multi-unsaturated and
mixed acid PC's.
All of the products are purified by HPLC, and special precautions
are taken to protect the products for oxidization and hydrolysis.
Several of these products are manufactured under cGMP guidelines
and are
available for pharmaceutical use. If you have a requirement
for a choline derivative not found on our list,
please call us: custom synthesis is one of our specialties.
Notes
Due to the high transition temperatures of the saturated products,
it may be necessary to heat the solvent to solubilize the compound.
Also, a small amount of methanol (0.1%) and water (0.05%) may be
needed to hydrate the compound.
Phosphatidylcholine (Asymmetric
Fatty Acid)
1-Acyl-2-Acyl-sn-Glycero-3-Phosphocholine
