|
Synthetic Products |
| Phosphatidylethanolamine |
|
Purity > 99% |
| Typical Phosphatidylethanolamine Structure |
|
|
|
1,2-Dimyristoyl-sn-Glycero-3-Phosphoethanolamine |
|
Specifications
for Purified Phosphatidylethanolamine |
| Physical Examination |
|
Powder: |
White solid which contains no foreign matter and no
more than a faint odor. |
|
Organic solution: |
Clear, colorless solution which contains no foreign
matter. |
| Identification |
|
GC: |
The retention time of the principal peak of the sample chromatogram
agrees with that of the chromatogram for the reference standard. |
|
TLC: |
The Rf value and general appearance of the principal
spot in the sample chromatogram agrees with that of the reference
standard. |
|
HPLC: |
The retention time of the principal peak of the sample chromatogram
agrees with that of the chromatogram for the reference standard. |
|
FTIR: |
The infrared absorption spectrum of the sample exhibits maxima only
at the same wavelengths as that of the standard between the regions
of 4000 - 500 cm-1. |
|
UV/Visible: |
The UV/Visible absorption spectrum of the sample exhibits maxima
only at the same wavelengths as that of the standard between the regions
of 190 - 820 nm. |
| Chromatographic Purity |
|
GC: |
Not less than 99.0% (AUC) |
|
HPLC: |
Not less than 99.0% (AUC) |
| Solubility |
| Short Chain (C6-C8) |
|
Soluble: |
Chloroform, Water |
|
Insoluble: |
Acetone |
| Long Chain Saturated (C10-C18) |
|
Soluble: |
Chloroform, Toluene |
|
Insoluble: |
Acetone, Methanol, Ethanol, Water |
| Long Chain Unsaturated (C10-C18) |
|
Soluble: |
Chloroform, Toluene |
|
Insoluble: |
Acetone, Methanol, Ethanol, Water |
| Stability |
|
Storage: |
-20°C |
|
Shelf Life: |
3 Months - Polyene
~ 6 Months - Monoene
~ 12 Months - Saturated |
Note
Due to high transition temperatures of saturated products, it may be necessary
to heat the solvent to solubilize the compound. Also, a small amount of
methanol (0.1%) and water (0.05%) may be needed to hydrate compound.
Description
The list of phosphatidylethanolamine products offered by Avanti is designed
to provide compounds having a variety of physical properties. Products
available include short chain (C6-C8; water soluble), saturated, multi-unsaturated and mixed acid PE,s. All of the products are purified by HPLC
and special precautions taken to protect the products from oxidation and
hydrolysis. Several products are manufactured under GMP guidelines and
are available for pharmaceutical use. If you have a requirement
for an ethanolamine derivative not found in this list, please call us.
References
- Rand, R.P., Fuller, N., Parsegian, V.A. & Tau,D.C., (1988), "Variation
in Hydration Forces Between Neutral Phospholipid Bilayers: Evidence
for Hydration Attraction", Biochemistry 27, 7711-7722
- Kung,V.T. & Redemann, C.T., (1986), "Synthesis of Carboxyacyl
Derivatives of Phosphatidylethanolamine and Use as an Efficient Method
for Conjugation of Protein to Liposomes", Biochim. Biophys.
Acta 862, 435-439
- Tate, M.W. & Gruner, S.M., (1987), "Lipid Polymorphism of
Mixtures of Dioleoylphosphatidylethanolamine and Saturated and Monounsaturated
Phosphatidylcholines of Various Chain Lengths", Biochemistry
26, 231-236
Phosphatidylethanolamine (Asymmetric Fatty Acid)
1-Acyl-2-Acyl-sn-Glycero-3-Phosphoethanolamine
|
Carbon
Number |
1-Acyl |
2-Acyl |
M.W. |
Catalog
Number |
|
|
16:0-18:1 |
Palmitoyl |
Oleoyl |
718.01 |
850757 |
|
|
16:0-18:2 |
Palmitoyl |
Linoleoyl |
715.99 |
850756 |
|
|
16:0-20:4 |
Palmitoyl |
Arachidonoyl |
740.01 |
850759 |
|
|
16:0-22:6 |
Palmitoyl |
Docosahexaenoyl |
764.04 |
850801 |
|
|
18:0-18:1 |
Stearoyl |
Oleoyl |
746.06 |
850758 |
|
|
18:0-18:2 |
Stearoyl |
Linoleoyl |
744.05 |
850802 |
|
|
18:0-20:4 |
Stearoyl |
Arachidonoyl |
768.07 |
850804 |
|
|
18:0-22:6 |
Stearoyl |
Docosahexaenoyl |
792.09 |
850806 |
|
Phosphatidylethanolamine (Symmetric Fatty Acid)
1,2-Diacyl-sn-Glycero-3-Phosphoethanolamine
| Carbon Number |
Product |
M.W. |
Catalog Number |
|
| 6:0 |
Dicaproyl |
411.43 |
850697 |
|
| 8:0 |
Dioctanoyl |
467.54 |
850699 |
|
| 10:0 |
Dicapryl |
523.64 |
850700 |
|
| 12:0 |
Dilauroyl |
579.76 |
850702 |
|
| 14:0 |
Dimyristoyl |
635.86 |
850745 |
|
15:0 |
Dipentadecanoyl |
663.92 |
850704 |
|
| 16:0 |
Dipalmitoyl |
691.97 |
850705 |
|
| 16:0[(CH3)4] |
Diphytanoyl |
804.19 |
850402 |
|
| 16:1 |
Dipalmitoleoyl |
687.93 |
850706 |
|
|
17:0 |
Diheptadecanoyl |
720.02 |
830756C |
|
|
17:0 |
Diheptadecanoyl |
720.02 |
830756P |
|
| 18:0 |
Distearoyl |
748.08 |
850715 |
|
| 18:1(delta 9-cis) |
Dioleoyl |
744.05 |
850725 |
|
| 18:1(delta 9-trans) |
Dielaidoyl |
744.05 |
850726 |
|
| 18:2 |
Dilinoeoyl |
740.01 |
850755 |
|
| 18:3 |
Dilinolenoyl |
735.98 |
850795 |
|
| 20:4 |
Diarachidonoyl |
788.06 |
850800 |
|
| 22:6 |
Docosa- hexaenoyl |
836.10
|
850797 |
|
Note: Polyenes may be packaged with BHT at user's request.
|
