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Lipid Products Bioactive Lipids Bioactive Ceramides
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C6-Pyridinium-Ceramide D-erythro-2-N-[6'-(1"-pyridinium)-hexanoyl]-sphingosine bromide 857450
  Data
ReferencesSeparovic, D., Bielawski, J., Pierce, J.S., Merchant, S., Tarca, A.L., Ogretmen, B., Korbelik, M. (2009). Increased tumour dihydroceramide production after Photofrin-PDT alone and improved tumour response after the combination with the ceramide analogue LCL29. Evidence from mouse squamous cell carcinomas. Br J Cancer. 100:626-32. [PubMed] Szulc, Z.M., Bielawski, J., Gracz, H., Gustilo, M., Mayroo, N., Hannun, Y.A., Obeid, L.M., Bielawska A. (2006). Tailoring structure-function and targeting properties of ceramides by site-specific cationization. Bioorg Med Chem. 14:7083-104. [PubMed]
Novgorodov, S.A., Szulc, Z.M., Luberto, C., Jones, J.A., Bielawski, J., Bielawska, A., Hannun, Y.A., Obeid, L.M. (2005). Positively charged ceramide is a potent inducer of mitochondrial permeabilization. J Biol Chem 280:16096-105. [PubMed]
Rossi, M.J., Sundararaj, K., Koybasi, S., Phillips, M.S., Szulc, Z.M., Bielawska, A., Day, T.A., Obeid, L.M., Hannun, Y.A., Ogretmen, B. (2005). Inhibition of growth and telomerase activity by novel cationic ceramide analogs with high solubility in human head and neck squamous cell carcinoma cells. Otolaryngol Head Neck Surg 132:55-62. [PubMed] Downloads
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